• Split-screen before-and-after of eczema-prone neck skin, showing visible redness and irritation on the left and calmer, smoother-looking skin on the right, with Treats Lab ABC Microbiome Calming Lotion being applied in both.
ABC Microbiome Calming Lotion

ABC Microbiome Calming Lotion

ABC Microbiome Calming Lotion

4.8
Rated 4.8 out of 5 stars
68 Reviews
$48.00 USD
$48.00 USD
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Daily Face Moisturizer for Sensitive, Reactive & Eczema-Prone Skin

A fast-absorbing, fragrance-free face moisturizer that delivers lasting hydration while helping soothe dryness, calm the look of redness, and support both the skin barrier and microbiome. Powered by Ceramide NP, Beta-Glucan, Copper Tripeptide-1, CICA, amino acids, and patented Bi-Om Complex™, it leaves dry, stressed skin feeling softer, smoother, and more comfortable without heaviness.

Awarded the Seal of Acceptance™ by the National Eczema Association.

Benefits

  • Calms
  • Hydrates
  • Smoothes

Size

50mL / 1.7fl oz

Treats skin that is:

  • Dry, Red, Irritated
  • Hypersensitive
  • Eczema-Prone

Formulated without:

  • Dyes
  • Fragrance
  • Gluten
  • Parabens
  • PEGs
  • Phthalates
  • Steroids
  • Sulfates

Microbiome Friendly Formulation

  • Hypoallergenic
  • pH Balanced
  • pH Level: 6-7
  • Vegan Ingredients
  • Cruelty-Free

How to use

Apply to clean skin as often as needed. Good for face and body; and as a spot treatment for visibly red and irritated areas.

Product Ingredients

Water, Glycerin, Dipropylene Glycol, C9-12 Alkane, Squalane, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Cetearyl Alcohol, Glyceryl Stearate SE, Arachidyl Alcohol, Sorbitan Stearate, Synthetic Beeswax, Propanediol, Polyglyceryl-10 Laurate, Dimethicone, Behenyl Alcohol, Tocopheryl Acetate, Arachidyl Glucoside, Carbomer, Tromethamine, Ethylhexylglycerin, Hydrogenated Lecithin, Xanthan Gum, Beta-Glucan, Ceramide NP, Copper Tripeptide-1, Glucose, Madecassoside, Centella Asiatica Leaf Extract, Asiaticoside, Alanine, Glycine, Arginine, Serine, Glutamic Acid, Coptis Japonica Extract, Scutellaria Baicalensis Root Extract, Houttuynia Cordata Extract, Dictamnus Dasycarpus Root Extract

Shipping & Returns

Shipping & Delivery

Orders ship from our U.S. warehouse within 1–2 business days.

We offer domestic and international shipping. International orders are shipped Delivered Duties Paid (DDP)—duties and taxes are collected at checkout so your order arrives without additional fees or delays.

Shipping rates and delivery estimates are calculated at checkout. You’ll receive tracking information as soon as your order ships.


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Why Every Formula Starts with Bi-Om Complex™

Bi-Om Complex™ is Treats Lab's signature patented technology, inspired by traditional Korean Hanbang medicine and developed for sensitive, reactive, and eczema-prone skin.

This proprietary blend combines four Korean botanicals selected for their long history of use in supporting skin comfort and balance.

Developed through patented Korean skin science, Bi-Om Complex™ helps support a healthy-looking skin barrier, a balanced skin microbiome, and calmer, more resilient-looking skin over time.

Explore Our Science

Beyond Bi-Om Complex™

  • AI AMINO PEPTIDES™— Peptides + Amino Acids for Skin Comfort

    A patented complex combining five amino acids with Copper Tripeptide-1 to support skin comfort and resilience. Helps skin feel calmer, smoother, and more balanced over time.

  • water droplets on surface representing centella asiatica skincare hydration and barrier support with visible centella benefits

    FULL-SPECTRUM CICA™— Complete Centella Support for Sensitive Skin

    A comprehensive Centella complex featuring the whole plant extract alongside Madecassoside and Asiaticoside. Helps support sensitive skin and promote a stronger-looking moisture barrier.

  • DUAL-MOIST™— Dual-Action Hydration for Lasting Comfort

    A patented combination of Beta-Glucan and Ceramide NP that helps attract moisture and lock it in. Helps keep skin feeling hydrated, soft, and comfortable throughout the day.

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Trusted by Sensitive Skin

  • ⭐️⭐️⭐️⭐️⭐️

    "I felt comfortable putting it on multiple times a day."

    Misha J.

  • ⭐️⭐️⭐️⭐️⭐️

    "The lotion is so gentle, fragrance free and most importantly, effective."

    HanNa W.

  • ⭐️⭐️⭐️⭐️⭐️

    "This is great lotion when I am feeling dry, redness, and itchy."

    Brandi L.

1 3

Customers Reviews

4.8
Rated 4.8 out of 5 stars
Based on 68 reviews
Total 5 star reviews: 56 Total 4 star reviews: 10 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 0
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68 reviews
  • Bella C.
    Verified Reviewer
    2 weeks ago
    Rated 5 out of 5 stars
    Calming

    I used this lotion whenever I felt I had irritation on my skin, specifically around my nose, chin, and forehead. I live in a very dry climate at high altitude and felt like this calming lotion made a difference in my skin’s calmness and hydration

    Was this helpful?
  • Allison L.
    Verified Reviewer
    1 month ago
    Rated 4 out of 5 stars
    So soothing

    I love the sensation of how this lotion feels on my skin! It’s so refreshing especially with the night time application!

    Was this helpful?
  • HanNa W.
    Verified Reviewer
    1 month ago
    Rated 5 out of 5 stars
    Gentle and effective

    I had been battling with eczema on my neck for months before I started using Treats Lab products. The ABC Microbiome Calming lotion was definitely calming to my skin and I could feel the relief almost immediately. It helped with the inflammation and the itchiness I was struggling with. Within a week I could see and feel a difference. After four weeks of continuous use, my skin is not red and not itchy. The patch of eczema is barely noticeable now. I will continue to use until the eczema is completely gone. The lotion is so gentle, fragrance free and most importantly - effective. I am very impressed with the results. Both the mist and the lotion will be my go-to products anytime I have eczema or skin irritation.

    Was this helpful?
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FAQ

Is the ABC Microbiome Calming Lotion safe for eczema-prone and sensitive skin?

Yes! ABC Microbiome Calming Lotion was designed specifically to help visibly address the atopic symptoms associated with sensitive skin, and has been accepted by the National Eczema Association. The lotion was formulated without known irritants and has been clinically tested and dermatologist approved for sensitive skin.

Is the ABC Microbiome Calming Lotion safe for acne-prone skin?

ABC Microbiome Calming Lotion was formulated using only non-comedogenic ingredients. It can be helpful to use between prescription acne treatments to help balance and heal the skin moisture barrier. 

What skin types is ABC Microbiome Calming Lotion best for?

ABC Microbiome Calming Lotion is especially helpful for skin that tends to feel easily stressed or out of balance, including:

sensitive skin
reactive-looking skin
eczema-prone skin
dry or compromised skin barrier

This microbiome-friendly formula is designed to help comfort visible irritation while supporting long-term skin balance.

What makes ABC Microbiome Calming Lotion different from other moisturizers for sensitive skin?

ABC Microbiome Calming Lotion supports both the skin barrier and the skin microbiome. Powered by three patented complexes alongside peptides, ceramides, and calming ingredients like CICA, the formula helps comfort stressed skin while supporting long-term skin balance. 

​​Rather than focusing only on hydration, it combines barrier-supporting lipids, amino acid peptides, and traditional Korean botanical extracts to help skin look calmer, smoother, and more resilient over time.

How does supporting the skin barrier help sensitive skin?

The skin barrier helps protect against moisture loss and external stressors. When the barrier becomes compromised, skin can feel dry, irritated, or reactive. Ingredients like ceramides, amino acid peptides, and calming botanicals help reinforce the barrier while hydrating ingredients replenish moisture, helping skin feel more comfortable, resilient, and balanced.

Can I use the ABC Microbiome Calming Lotion with actives?

ABC Microbiome Calming Lotion was formulated with calming, hydrating, and barrier strengthening ingredients to help with irritation that can be associated with use of actives or topical prescriptions. Though it should layer nicely with other actives, if you are trying a new combination, we recommend patch testing first.

Is the ABC Microbiome Calming Lotion safe to use if I am pregnant or breastfeeding?

The ABC Microbiome Calming Lotion does not include any ingredients that are known to be unsafe for pregnancy or breastfeeding, however, if you are concerned, please have your healthcare provider advise.

Can I use the ABC lotion under makeup?

Yes. The lightweight, fast-absorbing formula layers well under makeup, helping create a smooth, comfortable base without pilling or heaviness.